(Redirected from Ovarian neoplasms)
Benign ovarian cysts in reproductive-age women undergoing assisted reproductive technology treatment. Sive ovarian cancer was reported in patients with an. Other benign ovarian cysts, including perinatal outcomes, is favorable. The cysts should be managed conservatively. Methods: We studied 192 patients with epithelial ovarian cancer, 173 with benign ovarian tumors, 229 with benign gynecologic disease, and 405 healthy controls.
Ovarian tumors, or ovarian neoplasms, are tumors arising from the ovary. They can be benign or malignant (ovarian cancer).
Benign tumors[edit]
A benign tumor of the ovary, discovered during a C-section; this is a 4 cm teratoma
Benign tumors of the ovary include ovarian cysts, such as borderline tumor cysts.
Cancer[edit]
A pathological specimen of ovarian carcinoma.
Ovarian cancer is classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis.
- Surface epithelial-stromal tumours, also known as ovarian epithelial tumors, are the most common type of ovarian cancer. It includes serous tumour, endometrioid tumor, and mucinous tumour. They can be benign (cystadenoma) or malignant (cystadenocarcinoma). Less common tumors are malignant Brenner tumor and transitional cell carcinoma of the ovary.
- Sex cord-stromal tumor, including estrogen-producing granulosa cell tumor and virilizing Sertoli-Leydig cell tumor or arrhenoblastoma, accounts for 8% of ovarian cancers.
- Germ cell tumor accounts for approximately 30% of ovarian tumors but only 5% of ovarian cancers, because most germ cell tumors are teratomas and most teratomas are benign. Germ cell tumors tend to occur in young women (20s–30s) and girls. Whilst overall the prognosis of germ cell tumors tend to be favourable, it can vary substantially with specific histology: for instance, the prognosis of the most common germ cell tumor (dysgerminomas) tends to be good, whilst the second most common (endodermal sinus tumor) tends to have a poor prognosis. In addition, the cancer markers used vary with tumor type: choriocarcinomas are monitored with beta-HCG; dysgerminomas with LDH; and endodermal sinus tumors with alpha-fetoprotein.
- Mixed tumors, containing elements of more than one of the above classes of tumor histology.
Retrieved from 'https://en.wikipedia.org/w/index.php?title=Ovarian_tumor&oldid=909037773'
doi: 10.1289/ehp.877315
PMID: 3665859
This article has been cited by other articles in PMC.
Abstract
Most human ovarian tumors are classified into one of several categories based on presumed histogenesis and direction of differentiation. Separate categories are reserved for neoplasms composed of cells of several origins and for nonneoplastic disorders that simulate neoplasms. Using the World Health Organization Histologic Classification of Ovarian Tumors, histologic features for common and rare human ovarian tumors are described and illustrated.
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Selected References
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- Young RH, Dickersin GR, Scully RE. Juvenile granulosa cell tumor of the ovary. A clinicopathological analysis of 125 cases. Am J Surg Pathol. 1984 Aug;8(8):575–596. [PubMed] [Google Scholar]
- Young RH, Welch WR, Dickersin GR, Scully RE. Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. Cancer. 1982 Oct 1;50(7):1384–1402. [PubMed] [Google Scholar]
- Prat J, Bhan AK, Dickersin GR, Robboy SJ, Scully RE. Hepatoid yolk sac tumor of the ovary (endodermal sinus tumor with hepatoid differentiation): a light microscopic, ultrastructural and immunohistochemical study of seven cases. Cancer. 1982 Dec 1;50(11):2355–2368. [PubMed] [Google Scholar]
- Aguirre P, Scully RE. Malignant neuroectodermal tumor of the ovary, a distinctive form of monodermal teratoma: report of five cases. Am J Surg Pathol. 1982 Jun;6(4):283–292. [PubMed] [Google Scholar]
- Kleinman GM, Young RH, Scully RE. Ependymoma of the ovary: report of three cases. Hum Pathol. 1984 Jul;15(7):632–638. [PubMed] [Google Scholar]
- Young RH, Scully RE. Ovarian tumors of probable wolffian origin. A report of 11 cases. Am J Surg Pathol. 1983 Mar;7(2):125–135. [PubMed] [Google Scholar]
- Dickersin GR, Kline IW, Scully RE. Small cell carcinoma of the ovary with hypercalcemia: a report of eleven cases. Cancer. 1982 Jan 1;49(1):188–197. [PubMed] [Google Scholar]
- Scully RE, Barlow JF. 'Mesonephroma' of ovary. Tumor of Müllerian nature related to the endometrioid carcinoma. Cancer. 1967 Sep;20(9):1405–1417. [PubMed] [Google Scholar]
- Mostoufizadeh M, Scully RE. Malignant tumors arising in endometriosis. Clin Obstet Gynecol. 1980 Sep;23(3):951–963. [PubMed] [Google Scholar]
- THURLBECK WM, SCULLY RE. Solid teratoma of the ovary. A clinicopathological analysis of 9 cases. Cancer. 1960 Jul-Aug;13:804–811. [PubMed] [Google Scholar]
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